Volume 20, Issue 24 (3-2023)                   RSMT 2023, 20(24): 57-67 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Donyaei A, Rahimi M, Nabavi F. Association of Arterial Stiffness Following Glucose Uptake and Exercise with Baseline Vitamin D Levels in Inactive Men and Women. RSMT 2023; 20 (24) :57-67
URL: http://jsmt.khu.ac.ir/article-1-534-en.html
Shahrood University of Technology , adelldonyai@yahoo.com
Abstract:   (150 Views)
vitamin D deficiency is associated with many cardiovascular disorders. Arterial stiffness responses also depend on nutritional and exercise. Therefore, the study aimed to investigate the relationship between arterial stiffness response after glucose uptake and exercise with baseline levels of vitamin D in inactive men and women.
The present study was an analysis correlation study, and the subjects were 88 inactive men and women with an age range of 20 to 45 years. Vitamin D, body composition, and arterial stiffness, were measured. Subjects then ran for 30 minutes at 65% of maximum heart rate. Also, 75g of glucose was given to the subjects after 30 minutes of activity, 60 minutes after the of glucose consumption and arterial stiffness was measured. Data were analyzed using Pearson correlation test and analysis of variance with repeated measures at a significant level (P≤0.05).there was a negative and significant relationship between baseline levels of vitamin D and changes in CAVI in women (p=0.001 and r=-0.559) and in men a positive and significant relationship (p=0.005 and r=0.413).It seems that basal levels of vitamin D can be effective in the vascular response; due to little research, more research is need.
Full-Text [PDF 981 kb]   (72 Downloads)    
Type of Study: Research | Subject: sport physiology
Received: 2022/06/21 | Accepted: 2022/11/25 | Published: 2023/03/6

1. 1. Lim SS, Gaziano TA, Gakidou E, Reddy KS, Farzadfar F, Lozano R, et al. Prevention of cardiovascular disease in high-risk individuals in low-income and middle-income countries: health effects and costs. The Lancet. 2007;370(9604):2054-62. [DOI:10.1016/S0140-6736(07)61699-7]
2. Karkhah A, Karkhah M, Ghadimi R. An Overview on the Role of Nutrition and Food Groups in the Prevention of Cardiovascular Diseases. Journal of Babol University Of Medical Sciences. [Review]. 2017;19(3):66-73.
3. Mozos I, Malainer C, Horbańczuk J, Gug C, Stoian D, Luca CT, et al. Inflammatory markers for arterial stiffness in cardiovascular diseases. Frontiers in immunology. 2017;8:1058. [DOI:10.3389/fimmu.2017.01058]
4. Hughes TM, Craft S, Lopez OL. Review of 'the potential role of arterial stiffness in the pathogenesis of Alzheimer's disease'. Neurodegenerative disease management. 2015;5(2):121-35. [DOI:10.2217/nmt.14.53]
5. Mahdavi K, Amirajam Z, Yazdankhah S, Majidi S, Adel MH, Omidvar B, et al. The prevalence and prognostic role of vitamin D deficiency in patients with acute coronary syndrome: a single centre study in South-West of Iran. Heart, Lung and Circulation. 2013;22(5):346-51. [DOI:10.1016/j.hlc.2012.11.006]
6. Salim Bahram iS, Naghshtabrizi B, Borzouei S, Ahmadi Z. Comparison of Vitamin D Serum Level in Patients with Cardiac Ischemic and Control Group at the Heart Hospital of Hamadan City. Avicenna Journal of Clinical Medicine. [Original]. 2017;24(1):20-5. [DOI:10.21859/hums-24013]
7. Li YC, Kong J, Wei M, Chen Z-F, Liu SQ, Cao L-P. 1, 25-Dihydroxyvitamin D 3 is a negative endocrine regulator of the renin-angiotensin system. The Journal of clinical investigation. 2002;110(2):229-38. [DOI:10.1172/JCI0215219]
8. Rodriguez AJ, Scott D, Srikanth V, Ebeling P. Effect of vitamin D supplementation on measures of arterial stiffness: a systematic review and meta‐analysis of randomized controlled trials. Clinical Endocrinology. 2016;84(5):645-57. [DOI:10.1111/cen.13031]
9. Kwak JH, Choi Y-H. Sex and body mass index dependent associations between serum 25-hydroxyvitamin D and pulse pressure in middle-aged and older US adults. Scientific reports. 2021;11(1):1-10. [DOI:10.1038/s41598-021-88855-8]
10. Karand JC, Reis K, Stephano PF, Gargurevich N, Zhou J, Desderius B, et al. Sex‐dependent correlates of arterial stiffness in Tanzanian adults. Tropical Medicine & International Health. 2021;26(11):1494-502 [DOI:10.1111/tmi.13676]
11. DuPont JJ, Kenney RM, Patel AR, Jaffe IZ. Sex differences in mechanisms of arterial stiffness. British journal of pharmacology. 2019;176(21):4208-25. [DOI:10.1111/bph.14624]
12. Razzaghi A, Sadeghi H. Effect of Exercise-based Cardiac Rehabilitation on Coronary Artery Biomechanical Variables in Atherosclerotic Patients: A Systematic Review Study. The Scientific Journal of Rehabilitation Medicine. 2020;9(1):270-83.
13. Guimarães GV, Ciolac EG, Carvalho VO, D'Avila VM, Bortolotto LA, Bocchi EA. Effects of continuous vs. interval exercise training on blood pressure and arterial stiffness in treated hypertension. Hypertension Research. 2010;33(6):627-32. [DOI:10.1038/hr.2010.42]
14. Okamoto T, Masuhara M, Ikuta K. Effects of low-intensity resistance training with slow lifting and lowering on vascular function. Journal of human hypertension. 2008;22(7):509-11. [DOI:10.1038/jhh.2008.12]
15. Heffernan KS, Fahs CA, Iwamoto GA, Jae SY, Wilund KR, Woods JA, et al. Resistance exercise training reduces central blood pressure and improves microvascular function in African American and white men. Atherosclerosis. 2009;207(1):220-6. [DOI:10.1016/j.atherosclerosis.2009.03.043]
16. Tabara Y, Yuasa T, Oshiumi A, Kobayashi T, Miyawaki Y, Miki T, et al. Effect of acute and long-term aerobic exercise on arterial stiffness in the elderly. Hypertension Research. 2007;30(10):895-902. [DOI:10.1291/hypres.30.895]
17. Huang CL, Chen MF, Jeng JS, Lin LY, Wang WL, Feng MH, et al. Postchallenge hyperglycaemic spike associate with arterial stiffness. International journal of clinical practice. 2007;61(3):397-402. [DOI:10.1111/j.1742-1241.2006.01227.x]
18. Rajabi H, donyai a, Motamedi P, Dehkhoda MR. Effect of Aerobic Training on Blood Pressure, HbA1c and Arterial Stiffness in Postmenopausal Women with Type 2 Diabetes. Jundishapur Scientific Medical Journal. 2018;16(6):631-42.
19. Donyaei A, Taghiabadi FS, Gholami F. The effect of different intensities of aerobic exercise before glucose ingestion on subsequent central arterial stiffness in active and inactive women. Journal of Practical Studies of Biosciences in Sport. 2021:-.
20. Kobayashi R, Yoshida S, Okamoto T. Arterial stiffness after glucose ingestion in exercise-trained versus untrained men. Applied Physiology, Nutrition, and Metabolism. 2015;40(11):1151-6. [DOI:10.1139/apnm-2015-0131]
21. Kobayashi R, Sato K, Sakazaki M, Nagai Y, Iwanuma S, Ohashi N, et al. Acute effects of difference in glucose intake on arterial stiffness in healthy subjects. Cardiology Journal. 2021;28(3):446-52. [DOI:10.5603/CJ.a2019.0108]
22. Gómez-Marcos MÁ, Recio-Rodríguez JI, Patino-Alonso MC, Agudo-Conde C, Gómez-Sánchez L, Gomez-Sanchez M, et al. Cardio-ankle vascular index is associated with cardiovascular target organ damage and vascular structure and function in patients with diabetes or metabolic syndrome, LOD-DIABETES study: a case series report. Cardiovascular diabetology. 2015;14(1):1. [DOI:10.1186/s12933-014-0167-y]
23. Yambe T, Yoshizawa M, Saijo Y, Yamaguchi T, Shibata M, Konno S, et al. Brachio-ankle pulse wave velocity and cardio-ankle vascular index (CAVI). Biomedicine & pharmacotherapy. 2004;58:S95-S8. [DOI:10.1016/S0753-3322(04)80015-5]
24. Andrukhova O, Slavic S, Zeitz U, Riesen SC, Heppelmann MS, Ambrisko TD, et al. Vitamin D is a regulator of endothelial nitric oxide synthase and arterial stiffness in mice. Molecular Endocrinology. 2014;28(1):53-64. [DOI:10.1210/me.2013-1252]
25. Giallauria F, Milaneschi Y, Tanaka T, Maggio M, Canepa M, Elango P, et al. Arterial stiffness and vitamin D levels: the Baltimore longitudinal study of aging. The Journal of Clinical Endocrinology & Metabolism. 2012;97(10):3717-23. [DOI:10.1210/jc.2012-1584]
26. Al Mheid I, Patel R, Murrow J, Morris A, Rahman A, Fike L, et al. Vitamin D status is associated with arterial stiffness and vascular dysfunction in healthy humans. Journal of the American College of Cardiology. 2011;58(2):186-92. [DOI:10.1016/j.jacc.2011.02.051]
27. Savastio S, Pozzi E, Tagliaferri F, Degrandi R, Cinquatti R, Rabbone I, et al. Vitamin D and cardiovascular risk: which implications in children? International journal of molecular sciences. 2020;21(10):3536. [DOI:10.3390/ijms21103536]

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2023 CC BY-NC 4.0 | Research in Sport Medicine and Technology

Designed & Developed by: Yektaweb