تاثیر مکمل یاری کوتاه مدت کورکومین بر میزان مالون دی آلدئید، ظرفیت ضد اکسیدانی تام و پروتئین واکنشی C‌ سرم در پاسخ به آزمون آمادگی جسمانی تناوبی فیفا در کمک داوران مرد فوتبال

نویسندگان

دانشگاه خلیج فارس

چکیده
مقدمه: فعالیت‌های ورزشی شدید با التهاب و فشار اکسایشی همراه اند. هدف از پژوهش حاضر بررسی تأثیرآزمون آمادگی جسمانی تناوبی فیفا همراه مکمل کورکومین برمیزان MDA، TAC وCRP سرم در کمک داوران مرد فوتبال بود.

روش‏‌ها: در این مطالعه نیمه تجربی 20 کمک داور فوتبال(میانگین سن 75/3±56/28 سال، قد 21/4±179 سانتیمتر، وزن 08/7±78/72 کیلوگرم) به صورت داوطلبانه انتخاب و به طور تصادفی دردو گروه آزمون و آزمون+ مکمل قرار گرفتند.گروه آزمون+ مکمل علاوه بر آزمون فیفا روزانه 5 گرم کورکومین (2/5 گرم صبح و2/5 گرم بعد از ظهر) به مدت پنج روز دریافت کردند. نمونه گیری خونی در سه مرحله (پیش ازمکمل دهی در دو نیم روز قبل، بلافاصله بعد و 48 ساعت پس از آزمون آمادگی جسمانی تناوبی فیفا ) انجام شد و متغیرها به روش اسپکتروفتومتری اندازه گیری و داده ها به وسیله آزمون تحلیل واریانس با اندازه گیری تکراری و آزمون تعقیبی بونفرونی تحلیل شدند.

یافته‌ها: یافته‌ها افزایش معنی دارCRP، MDA،TAC سرم در هر دو گروه را در پس آزمون اول نشان داد (000=0 P ، 041/0=P، 008/0= P، 009/0P=، 048/0P=، 014/0P=). در پس آزمون دوم گروه آزمون،افزایش یافته ها در میزانCRPو MDA همچنان معنی دار باقی ماند(000/0= P 022/0 P= اما TAC به افزایش غیر معنی دار تبدیل شد(160/0 P=)، در حالی که میزان افزایش آن در گروه آزمون+مکمل همچنان معنادار بود (013/0=P) و در گروه آزمون+مکمل میزان MDA به افزایش غیر معنی دار در مقایسه با پیش آزمون تبدیل شد(186/0=P). همچنین بین دو گروه تفاوت معنی داری در مقادیرCRP و TAC(024/0 P=، 05/0 P=) و تفاوت غیر معنی داری در میزان MDA وجود داشت(129/0P=).

نتیجه‌گیری: مکمل یاری کوتاه مدت کورکومین بخشی از شاخص های التهابی و اکسایشی ناشی از فعالیت استقامتی(آزمون فیفا) را تعدیل می کند.

کلیدواژه‌ها


عنوان مقاله English

Impact of Short-term Curcumin Supplementation on Level of Serum CRP, MDA and TAC in Response to FIFA Interval Physical Fitness Test in Male Football Assistant Referees

نویسندگان English

sara zare karizak
zaynab teimouri
Abdosaleh Zar
Persian Gulf University
چکیده English

Introduction



High-Intensity exercise is accompanied by inflammation and oxidative stress. This study aimed to investigate the effect of the FIFA test with curcumin supplementation on serum MDA, TAC, and CRP in male football assistant referees.

Method

In this semi-experimental study, 20 football assistant referees (mean age 28.56±3.75 years, height 179±4.21 cm, weight 72.78±7.08 kg) were selected voluntarily then were randomly assigned to the curcumin + FIFA test and the FIFA test groups. The test + supplement group, in addition to FIFA tests, received 5 grams of curcumin daily (2.5gram at morning and 2.5 gram at evening) for five days. Blood sampling was performed in three stages (before supplementation, two and a half day before, immediately after, and 48 hours after the FIFA Interval Physical Fitness Test) and serum levels of variables were measured using the spectrophotometric method. Repeated-measures ANOVA and Bonferoni post hoc tests were performed in SPSS26.



Results

There was significant increase in serum CRP, MDA, and TCA in both groups in the first post-test (P=0.000, P=0.041, P=0.008, P=0.009, P= 0.048, P=0.014). Also, in the second post-test of the test group, the increase in CRP and MDA levels remained significant (P = 0.000, P = 0.022). However, TAC became a non-significant increase (P=0.160), while its increase in the test + supplement group was still significant (P=0.013), and in the test + supplement group, MDA became a non-significant increase compared to the pre-test (P=0.186), while in the test group it still had a significant increase (P=0.022). In addition, there was a significant difference between the groups in CRP and TAC values ​​(P=0.024, P=0.05) and a non-significant difference in MDA levels (P=0.129).



Conclusion

Curcumin modulates some of the inflammatory and oxidative stress indices induced by endurance exercise (the FIFA test).

کلیدواژه‌ها English

Male Football Assistant Referees
FIFA interval physical fitness test
Curcumin
Malondialdehyde (MDA)
C-reactive protein (CRP)
Total Antioxidant Capacity (TAC)
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  • تاریخ دریافت 04 مرداد 1405
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