RT - Journal Article T1 - The effects of eight weeks resistance training on α -1A protein of pre-synaptic P-Q-type calcium channels in FHL and soleus muscles of rats JF - Research-in-Sport-Medicine-and-Technology YR - 2012 JO - Research-in-Sport-Medicine-and-Technology VO - 10 IS - 4 UR - http://jsmt.khu.ac.ir/article-1-76-en.html SP - 1 EP - 9 K1 - Resistance training K1 - α -1A protein K1 - Pre-synaptic P-Q-type calcium channels K1 - FHL and Soleus Muscle AB - The purpose of this study was to investigate the effects of 8 weeks resistance training (RT) on α -1A protein of pre-synaptic P-Q-type Calcium Channels in FHL and soleus muscles of rats. 16 male wistar rats provided from razi institute, randomly divided to 2 groups (Control-Sham; n=8 and Resistance Training; n= 8). Training group conducted 8 weeks (5 session/week) resistance program on special 1 meter height ladder (divided by 26 stairs) with loading 30% body weight (suspended from the tail) in the first week and increased to 200% BW in the last week. Training includes 3 set of 4 reps. with 3 min. rest between sets. Measuring α -1A protein with Western Blotting and independent T test showed that the amount of this protein insignificantly increased in FHL muscles of RT group (FHL: 77.88±10.67 vs. Control: 70.01± 6.28 and soleus: 72.71±19.72 vs. Control: 72.57 ± 20.20). This insignificant increase in α -1A protein in FHL, can shows an responsiveness of pre-synaptic P-Q-type Calcium Channels of muscles following resistance training for improving Ach release from presynaptic terminal, noted in NMJ adaptations . In conclusion, we can express that probably resistance training can be a main factor for α -1A protein improving in muscles and this case should be study in future investigations with high volume and intensities training LA eng UL http://jsmt.khu.ac.ir/article-1-76-en.html M3 ER -